Bone turnover markers
The two reference markers
| Marker | Reflects | |
|---|---|---|
| Resorption | serum CTX (beta-CrossLaps, C-telopeptide of type I collagen) | Osteoclast activity |
| Formation | serum P1NP (procollagen type I N-propeptide) | Osteoblast collagen synthesis |
- Others: NTX (urine), TRAP-5b, bone-specific ALP, osteocalcin. CTX and P1NP are the IOF/IFCC reference markers - use them rather than a miscellany
12 more sections, plus exam facts
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