Chronic renal failure - mineral and bone disorder
Description
- Systemic disorder of mineral and bone metabolism in CKD - not just a bone disease
- Three components, any combination:
- 1. Biochemical - Ca, PO4, PTH, vitamin D, FGF-23 abnormalities
- 2. Bone - renal osteodystrophy (turnover, mineralisation, volume)
- 3. Vascular/soft-tissue calcification
- The vascular component is what kills - calcification predicts cardiovascular mortality more strongly than fracture predicts anything
6 more sections, plus exam facts
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