Cutaneous manifestations of systemic diseases - acne
Description
- Acne as a sign pointing to an underlying systemic driver, rather than primary acne vulgaris of adolescence (see standalone acne note for routine disease/topical-to-isotretinoin management)
- Red flags for a systemic cause: sudden severe onset, onset outside the typical teenage window, resistance to standard therapy, or accompanying virilisation/systemic symptoms
- Two broad categories: androgen-excess acne and drug-induced acne
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