Hepatitis A
Description
- Picornavirus, non-enveloped RNA virus; faecal-oral transmission
- ACUTE ONLY - never chronic, no carrier state
- Clinical course: prodrome -> icteric phase -> recovery
- Prodrome: anorexia, nausea/vomiting, abdominal pain, fever, malaise - lasts about 7-14 days
- Anicteric in most children <6 (>70%); icteric in most adults (>70%)
- Severity increases with age - the defining epidemiological feature
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