Hepatitis - alcohol induced
Description
- Alcohol-related liver disease is a spectrum: steatosis -> alcoholic (steato)hepatitis -> fibrosis -> cirrhosis
- Steatosis is reversible in weeks; cirrhosis is not
- Alcohol-associated hepatitis = a clinical syndrome, not a biopsy finding
- Rapid-onset jaundice (<8 weeks) in a patient with heavy alcohol use (>40-60 g/day for >6 months, abstinent <60 days)
- AST >50 but usually <400, AST:ALT >1.5-2, bilirubin >50 micromol/L
- No other cause of liver disease
- Renamed "alcohol-associated" in newer nomenclature; MetALD describes coexisting metabolic and alcohol-related disease
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