RheumatologyTier 2Topic

Extra-articular manifestations of rheumatic disease - internal organ manifestations

Overview

  • Systemic inflammatory rheumatic diseases frequently involve internal organs beyond the joints - pulmonary, cardiac, renal, and GI manifestations are common and, in many conditions, drive prognosis and mortality more than the articular disease itself
  • Extra-articular organ involvement occurs across most systemic inflammatory rheumatic diseases (RA, SLE, systemic sclerosis, vasculitis), with the specific pattern varying by underlying condition

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