OncologyTier 1Disease (DEADMAN)

Metastatic disease manifestations - hypercalcaemia of malignancy

Description

  • Commonest metabolic complication of malignancy - 20-30% of cancer patients at some point
  • A marker of advanced disease and, historically, of a poor prognosis
  • Distinguish from primary hyperparathyroidism: malignancy is acute, severe and symptomatic; PHPT is chronic, mild and incidental

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