NeurologyTier 2Topic

Concept of ‘brain death’

Definition

  • Death determined by neurological criteria - a legal and clinical determination of death, not of a state of severe injury
    • *The patient is dead. Ventilation and circulation continue mechanically; the person does not*
  • Australian and New Zealand (ANZICS) definition: irreversible cessation of ALL function of the WHOLE brain, INCLUDING the brainstem
    • *Contrast the United Kingdom, which uses a BRAINSTEM-only formulation of death*
    • Clinical testing in both jurisdictions nonetheless rests on demonstrating absent brainstem reflexes and apnoea - the difference is conceptual, and it is what the exam asks
  • Australian law defines death as either:

1. Irreversible cessation of all function of the brain, OR

2. Irreversible cessation of circulation of blood in the body

  • Distinguish from
    • Coma - unarousable unresponsiveness, brainstem function present
    • Persistent vegetative state - wakefulness without awareness; brainstem intact, sleep-wake cycles present. NOT death
    • Minimally conscious state - inconsistent but reproducible purposeful behaviour
    • Locked-in syndrome - ventral pontine lesion; fully aware, quadriplegic and anarthric, communicating by vertical eye movement and blinking. NOT death, and catastrophic to mistake

16 more sections, plus exam facts

Premium unlocks every note across every specialty, and the full exam fact library behind it.

Get premium access