Renal transplantation issues - short and long-term complications, including management of BK virus nephropathy, diarrhoea, and neutropenia
Complications by time since transplant
- Complications sort by time since transplant - and the timeline is the diagnostic tool
| Period | Dominant problems |
|---|---|
| <1 month | Surgical (bleeding, leak, lymphocele, vascular thrombosis), delayed graft function, hospital-acquired infection (wound, line, UTI, C. difficile), hyperacute/acute rejection |
| 1-6 months | Opportunistic infection - CMV, BK, PJP, nocardia, listeria, aspergillus, TB reactivation, acute rejection, drug toxicity |
| >6 months | Community-acquired infection, chronic antibody-mediated rejection, CNI nephrotoxicity, malignancy, cardiovascular disease, recurrent disease, PTDM |
- *Cardiovascular disease is the leading cause of long-term death* - pre-existing risk plus hypertension, dyslipidaemia and post-transplant diabetes from the immunosuppression itself
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