Transfusion-related acute lung injury
Description
- Non-cardiogenic pulmonary oedema within 6 hours of transfusion
- Acute hypoxaemia + bilateral infiltrates + no evidence of left atrial hypertension or circulatory overload
- Hypotension is characteristic (whereas TACO gives hypertension)
- Often with fever, rigors, transient leucopenia
- *The commonest cause of transfusion-related death before haemovigilance-driven donor deferral; still a leading cause*
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